Kratom is made from the Mitragyna speciosa plant, which is a relative of the coffee plant. The substance has been used by communities for hundreds of years in tropical regions of southern Asia where the plant is native to. They have used it to increase mental energy and mental acuity, for improving sex drive, for enhancing mood, for relaxing the mind, and for pain.
Of late, more and more people in the Western World have developed an interest in the natural remedy. This is after anecdotal evidence emerged in news reports and online about how effective Kratom is in alleviating pain.
However, there are doubting Thomases who will not believe it until they see evidence in terms of research or when someone close to them actually uses the remedy and gets the expected results. This is perhaps because of the fact that most of us in the Western World are so used to “civilized” pharmaceutical drugs that we no longer believe in the therapeutic benefits of herbs and plants. Yet, ironically, it is from the plants and herbs that modern capsules, solutions and other medicines are made.
Nevertheless, in this article, we are going to give all doubting Thomases the evidence they need to believe that this natural remedy can work to reduce serious pain.
Kratom’s mechanism of action for pain relief
Kratom is a fantastic natural medicine (although there is no Kratom-based medicine approved by Health Canada as of now, everything you buy should not be advertised as medicine for it to be legal). It comes from the Mitragyna speciosa plant. The plant’s leaves are normally plucked when mature and dried. They are then ground to a fine powder before being packaged and shipped to manufacturing facilities where they are screened for contaminants and chemically profiled to establish the compounds present and their concentration.
In terms of the mechanism of action, the two chemical compounds that must be present in Kratom for it to work are 7-hydroxymitragynine and mitragynine. These chemical compounds are referred to as alkaloids and they are extremely powerful. They are powerful in the sense that they can interact with part of the brain to bring positive results.
The interaction is with opioid receptors found in the brain, GIT (Gastrointestinal tract), and the spinal cord. When the alkaloids bind to the receptors, they severely reduce the communication of pain signal to the brain, hence considerably reduces the amount of pain your brain will register. In a nutshell, mitragynine and 7-hydroxymitragynine work by blocking transmission of pain messages along the central nervous system.
Powerful pain-relief injections such as morphine, codeine, hydrocodone, and oxycodone work in the same way. These injections are given to block the transmission of pain signals along your nervous system.
And we all know that the likes of morphine are very effective at alleviating serious pain. Why then can’t Kratom also alleviate similar pain if it works the same way by affecting the very same processes? There is no reason. In fact, animal studies suggest that Kratom is actually more powerful than morphine at reducing pain. That just goes to show you that Kratom has a high potential of relieving your of acute pain or chronic pain than its synthetic alternatives such as morphine and codeine that also happen to be extremely addictive.
However, as always, this article is for informational purposes only and you should not take it as medical advice. So don’t stop any form of treatment involving opioids in place of Kratom on the basis of this article. You’ve got to consult a doctor or any other qualified medical professional to help you make the right decision.
If Kratom can kill pain then why is it not being sold as medicine?
There are two main reasons for this. The number one reason is that it will be illegal to sell Kratom as medicine because Health Canada has not approved any medicine containing Kratom.
Health Canada is the body charged with regulating drug and health products in the country. They approve drugs after a lengthy and expensive process that may go on for a couple of months or years. The process of drug approval involves researching, animal trials, clinical trials and so on. Nobody has yet done it for Kratom or for its alkaloids as far as we know. Therefore, nobody can legally sell it as medicine because there is no such medicine as of now.
However, the law says, that it is a medicine if it is consumable. Therefore, the people selling Kratom as of now are selling it for aromatic or botanical purposes but they know what the Kratom is being used for.
Secondly, Kratom isn’t being sold as medicine because big pharma have their old medicines for pain that they have been peddling around the globe for ages. The pain medicines (analgesics) are their money-makers because everybody uses them. However, therefore, it is not in their best interest to see more powerful Kratom-based medicines. Thus, it is our belief that they may be working to stop the success of such medicines by other manufacturers.
Kratom is truly an analgesic based on the evidence provided in this article. It blocks pain transmission signals in the same way as morphine and codeine, and it is even more powerful than morphine as an analgesic. Although the botanical agent is not yet registered as a drug with Health Canada, it can still be sold for purposes other than medical purposes. Those who buy it can then decide on how to use it; whether they will use it for therapeutic purposes or not. However, before you make the choice, make sure you consult with your doctor or any other qualified medical professional.